Extensive Cancer Screening Following Unprovoked VTE
Marc Carrier, MD, from the University of Ottawa discusses his late-breaking presentation from ISTH 2015 regarding screening for cancer following unprovoked VTE. This trial of 854 patients randomized to receive age/gender-specific cancer screening only or age/gender-specific screening plus CAT scan of the abdomen and pelvis with virtual colonoscopy and gastroscopy. Patients were followed for 12 months, and overall the prevalence of cancer detection was found to be lower than previously described. Extensive cancer screening following unprovoked VTE was no better at detecting more cancers or detecting missed cancers, and there was no significant difference noted in overall survival or other secondary endpoints between groups. The authors concluded that unprovoked VTE should not warrant extensive screening at this point, and that healthcare resources would be better directed to more high risk patients who require more extensive screening.